By pressing ctrl + p you can open up a search box which will search all of the files in your project for whatever you type into it. If you spend time searching through the hundreds of nested folders in your sidebar to find a particular file then you are wasting time that can be saved by a keyboard shortcut. Also, if you do not have any code highlighted at all when pressing this shortcut it will comment out the line your cursor is on which is really useful for quickly turning on or off logging statements.
This can be tedious to do manually which is why most editors allow you to comment out all of the code on the lines you have highlighted by pressing ctrl + /. When you are writing or debugging code you commonly need to comment out individual sections/lines. This is probably the shortcut I use the most. You can do the same thing with ctrl + x to cut a line and paste it somewhere else which is incredibly useful. Then if you press ctrl + v it will paste the entire line directly above the line your cursor is currently on. If you just place your cursor on a line without highlighting anything and press ctrl + c it will copy the entire line your cursor is on including the line break. You are probably already familiar with how to cut/copy/paste highlighted sections of code by using ctrl + x, ctrl + c, and ctrl + v respectively, but you can actually take this a step further by copying an entire line at a time.